Van de Ven Double Halts Everton's Run at New Home Ground
Micky van de Ven emerged as the first backline player to score two goals in a English top-flight game for Spurs since Jan Vertonghen in March 2013.
Key points
Micky Van de Ven heads home twice in first half
The home side's Jake O'Brien has equalizer disallowed after VAR review
Senegalese midfielder nets third in dying moments
This loss is the Merseyside club's initial at Hill Dickinson Stadium
Micky van de Ven found the net on two occasions as Tottenham prolonged their unbeaten run on the road in the top division and handed Everton their first defeat at their new home.
Everton were undefeated in their five previous fixtures at their recently opened stadium at Bramley-Moore Dock, having left Goodison Park behind after 133 years at the conclusion of last season.
But Spurs captain the Dutchman struck twice from set-pieces in the first half to place their strong form at jeopardy, and they were failed to mount a comeback before Pape Matar Sarr - set up by ex-Everton forward the Brazilian - nodded in a final goal to put the game to bed.
The Everton defender thought he had equalized the tally a short while after the defender's first goal, glancing a bullet header past the Spurs keeper from an Everton corner.
The Portuguese striker, meanwhile, missed a handful of opportunities, while the Italian goalkeeper made a series of excellent saves to ensure the London club went five matches on the road unbeaten in the Premier League.
But the VAR intervened, instructing the match official to review the goal on the screen and the official decided that Jack Grealish and the attacker were in offside positions and had interfered with the Tottenham goalkeeper.
This victory elevates the manager's side into third place in the Premier League, five points off north London rivals and table-toppers the Gunners.
Everton stay in 14th position and sit half a dozen points clear of the relegation zone.
Spurs breakdown: The defender fulfils role at each end of the field
After a drab midweek display in the European competition against Monaco, where they managed a only two shots on target, Frank opted for Randal Kolo Muani up front instead of former Toffees player the Brazilian.
The summer signing was unable to make much of an impact before being substituted for Richarlison after an hour on the field, but it emerged he wasn't needed in the final outcome.
Centre-back Van de Ven transformed into an attacking force to be reckoned with.
Spurs' opening strike came from a cleverly executed set-piece play, with the midfielder heading the ball toward the face of goal for an free the defender to head home.
And the captain - filling in as skipper in the Argentine's absence - added his next goal in added time as he rose above Jordan Pickford to nod in.
The Dutchman was equally impressive in defence, partnering well with his defensive colleague as the pair dealt superbly with the 34 crosses thrown their way by the opposition.
Everton analysis: Toffees lacking striker's instinct
The club's new home had been a fortress, but it appears the novelty may have faded slightly and fans flocked to the exits after Sarr's third for Tottenham.
The end in the team's winning streak at home won't be a major concern for David Moyes, but their striker situation will be.
The forward and the other striker - the Everton's two recognised centre-forwards - had netted only a single goal between them before the weekend's match.
And they were unable to contribute to that poor record on a damp and dreary night on in Liverpool.
Beto's performance was summed up when he chose to bicycle-kick a clear chance from near the goal, even with having space and time to reposition for a more conventional attempt that would have challenged Vicario.
Barry, as well, was unable to make an impact after coming on for the starter in the 65th minute.
It was not for a shortage of opportunity. Most of the home side's attacks came through the winger and the forward, who tirelessly whipped threatening crosses into the Spurs penalty area.
Upcoming fixtures for these two sides?
The Toffees: Moyes' men travel to Sunderland in the Premier League on early November at 20:00 GMT.
Tottenham: The London club travel to Newcastle's ground on Wednesday, 29 October for their fourth-round League Cup tie against Newcastle.